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SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).
| Gene Name: | solute carrier family 16 (monocarboxylate transporter), member 3 |
| Family/Subfamily: | Transporter , Monocarboxylic acid transporter |
| Synonyms: | SLC16A3, MCT 3, MCT-4, MCT3, MCT4, Monocarboxylate transporter 4, MCT-3, Monocarboxylate transporter 3, MCT 4 |
| Target Sequences: | NM_004207 NP_004198.1 O15427 |
Publications (1)
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