SIRT1 / Sirtuin 1

sirtuin 1

The SIRT family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes including transcriptional regulation, cell cycle progression, DNA damage repair and aging. Sirtuins utilize NAD+ as a substrate to catalyze deacetylation of specific acetylated protein and histones. SIRT1 has been shown to be induced by caloric restriction (CR) in several tissues and SIRT1 mediated deacetylase activity attenuates B-amyloid content in the brain during CR. SIRT1 also regulates the p53-dependent DNA damage response pathway by binding to and deacetylating p53.

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Products

Proteins (11)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (3)

Recombinant (7)

Target

SIRT1 / Sirtuin 1 (11)

Publications

No (11)

Tag

6His, N-terminus (2)

8His, N-terminus (1)

GST, N-terminus (1)

His (4)

Myc-DDK (Flag) (3)

Species

Human (8)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (4)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human SIRT1 / Sirtuin 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88786

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

81.5 kDa

Price:

20 µg/$215

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Human SIRT1 / Sirtuin 1 Protein (Recombinant His) - LS-G2840

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human SIRT1 / Sirtuin 1 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Ile2-Ser555) - LS-G26858

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

63.3 kDa

Price:

200 µl/$283

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Human SIRT1 / Sirtuin 1 Protein (Over-Expression Lysate 8His, N-terminus) (Ile2-Ser555) - LS-G26719

Source:

HEK 293 Cells

Tag:

8His, N-terminus

Molecular Weight:

63.3 kDa

Price:

100 µg/$298

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Human SIRT1 / Sirtuin 1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71105

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

81.5 kDa

Price:

20 µg/$1,107

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Human SIRT1 / Sirtuin 1 Protein (Recombinant 6His, N-terminus) (aa2-747) - LS-G56830

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human SIRT1 / Sirtuin 1 Protein (Recombinant GST, N-terminus) (aa456-555) - LS-G61989

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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SIRT1 / Sirtuin 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101057

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

81.5 kDa

Price:

100 µg/$710

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Human SIRT1 / Sirtuin 1 Protein (Recombinant His) (aa244-498) - LS-G15580

Source:

E. coli

Tag:

His

Molecular Weight:

30.3 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Mouse SIRT1 / Sirtuin 1 Protein (Recombinant His) (aa236-490) - LS-G15582

Source:

E. coli

Tag:

His

Molecular Weight:

30.3 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900

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Rat SIRT1 / Sirtuin 1 Protein (Recombinant His) (aa238-482) - LS-G15583

Source:

E. coli

Tag:

His

Molecular Weight:

29.2 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,521

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