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Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Gene Name: | SIN3 transcription regulator family member B |
Synonyms: | SIN3B, KIAA0700 |
Target Sequences: | AK001633 BAA31675.2 O75182 |
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