SIGLEC12

Sialic acid binding Ig-like lectin 12

Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternative splicing results in multiple transcript variants.

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Products

ELISA Kits (8)

Type

Sandwich (8)

Target

SIGLEC12 (8)

Reactivity

Human (2)

Mouse (1)

Chicken (1)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Format

96-Well Strip Plate (8)

Publications

No (8)

Sample Type

Plasma (3)

Serum (3)

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Chicken SIGLEC12 (Sandwich ELISA) ELISA Kit - LS-F48010

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

1.563 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig SIGLEC12 (Sandwich ELISA) ELISA Kit - LS-F48011

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1.563 - 100 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Monkey SIGLEC12 (Sandwich ELISA) ELISA Kit - LS-F48012

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit SIGLEC12 (Sandwich ELISA) ELISA Kit - LS-F48014

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

1.25 - 80 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine SIGLEC12 (Sandwich ELISA) ELISA Kit - LS-F48013

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Human SIGLEC12 (Sandwich ELISA) ELISA Kit - LS-F27224

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

100 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Human SIGLEC12 (Sandwich ELISA) ELISA Kit - LS-F38021

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse SIGLEC12 (Sandwich ELISA) ELISA Kit - LS-F38417

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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