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Sialylated Lewis a / CA 19-9

Sialylated Lewis Antigen (CA19-9,Carbohydrate antigen, FUT) is a tetrasaccharide that constitutes the sialytated form of Lewis Antigen A. CA19-9 attaches to O-glycans on the plasma membrane where it functions in intercellular recognition. It is a common pancreatic and metastatic colorectal cancer marker because it shows elevated levels alongside CEACAM5 (CEA) expression in late tumors (Vukobrat-Bijedic, 2013; Polat, 2014). CA19-9 is an effective marker for circulating tumor cells, as increased levels of CA19-9 in serum coincide with the quantity of circulating tumor cells from colorectal metastases (Zhao, 2017). Pre- and post treatment levels of CA19-9 are also used as a guage for the efficacy of a given therapy and as a red flag for reoccurrence. In immunohistochemistry, staining of antibodies to CA19-9 is primarily cytoplasmic.

Sialylated Lewis a / CA 19-9 Target Details

Target Name: Sialylated Lewis a / CA 19-9

Publications (2)

1
Potentials and capabilities of the Extracellular Vesicle (EV) Array. Jørgensen MM, Bæk R, Varming K. Journal of Extracellular Vesicles. 2015 4:26048. (IHC; Human) [PubMed:25862471] [PMC:PMC4393420] Related Antibodies: LS-B5680.
2
Profiling of different pancreatic cancer cells used as models for metastatic behaviour shows large variation in their N-glycosylation. Holst S, Belo AI, Giovannetti E, van Die I, Wuhrer M. Scientific reports. 2017 November;7:16623. (Human) [Full Text Article] [PubMed:29192278] [PMC:PMC5709460]

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Sialylated Lewis a / CA 19-9 (6)
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Cell Culture Supernatants (2)
Cell Lysates (1)
Plasma (6)
Serum (6)
Tissue Homogenates (2)
Sialylated Lewis a / CA 19-9 ELISA Kit
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Sandwich
96-Well Microplate
Human
10 - 150 U/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$782
Sialylated Lewis a / CA 19-9 ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
5 - 100 U/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
Sialylated Lewis a / CA 19-9 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
3.125 - 200 IU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sialylated Lewis a / CA 19-9 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.3 - 200 U/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
Sialylated Lewis a / CA 19-9 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.781 - 50 U/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$685
Sialylated Lewis a / CA 19-9 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
3.125 - 200 U/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).