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Negative regulator of PARK2 translocation to damaged mitochondria. Acts probably by destabilizing PINK1 protein, hence inhibiting PARK2 targeting to dysfunctional depolarized mitochondria.
Gene Name: | siah E3 ubiquitin protein ligase family member 3 |
Synonyms: | SIAH3, Seven in absentia homolog 3, Siah-3 |
Target Sequences: | NM_198849 NP_942146.2 Q8IW03 |
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