SHOX

short stature homeobox

The pseudoautosomal region (PAR1) contains an interval of 170 kb that tends to be deleted in individuals with short stature and different rearrangements on Xp22 or Yp11.3. SHOX (Short stature HOmeoboX-containing gene) a homeo box-containing gene located in the PAR1, has at least 2 alternatively spliced forms encoding proteins with different patterns of expression. SHOX is involved in idiopathic growth retardation and in the short stature phenotype of Turner syndrome patients. The 2 mRNAs, SHOXa and SHOXb, code for proteins of 292 and 225 amino acids, respectively. Both transcripts have a common 5&#039 end, diverging after exon IV. The SHOX gene is composed of 6 exons ranging in size from 58 bp to 1146 bp. SHOX is highly conserved across species. The absence of the SHOX gene may be responsible for the growth failure in Turner syndrome females.

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Proteins (3)

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Over-Expression Lysate (2)

Recombinant (1)

Target

SHOX (3)

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Myc-DDK (Flag) (3)

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Human (2)

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293T Cells (1)

HEK 293 Cells (2)

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SHOX Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123177

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.1 kDa

Price:

100 µg/$494

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Human SHOX Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69742

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.1 kDa

Price:

20 µg/$1,107

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Human SHOX Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85443

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.1 kDa

Price:

20 µg/$150

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