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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
Contact Us
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SHANK2 / SHANK

SH3 and multiple ankyrin repeat domains 2

SHANK2 / SHANK is a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density of excitatory synapses. Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, and an SH3 domain. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the postsynaptic densities of the adult and developing brain. Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder. Alternative splicing results in multiple transcript variants.

Gene Name: SH3 and multiple ankyrin repeat domains 2
Synonyms: SHANK2, AUTS17, Cortactin binding protein 1, CTTNBP1, CORTBP1, SPANK-3, SHANK, Cortactin-binding protein 1, GKAP/SAPAP interacting protein, KIAA1022, ProSAP1
Target Sequences: NM_012309 NP_036441.2 Q9UPX8


SHANK2 / SHANK Antibody - Anti-SHANK2 / SHANK antibody IHC staining of human intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal (IgG) to Human SHANK2 / SHANK
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
SHANK2 / SHANK Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Rabbit Polyclonal (IgG) to Human SHANK2 / SHANK
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $425.00
SHANK2 / SHANK Antibody - Western blot analysis of Shank2 in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone S23b-6] (IgG1) to Rat SHANK2 / SHANK
Rat, Human
ICC, IHC, IP, WB
Unconjugated
100µg   $365.00
SHANK2 / SHANK Antibody - Western blot analysis of Shank2 in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone S23b-6] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 390 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of Shank2 in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone S23b-6] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 488 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of Shank2 in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone S23b-6] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 565 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of Shank2 in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone S23b-6] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 633 Conjugated
100µg   $395.00
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Human SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100µg   $425.00
SHANK2 / SHANK Antibody - Brain membranes from whole rat (RBM) and mouse (MBM) brain and from human (HBM) cerebral cortex and hippocampus.
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Mouse Monoclonal [clone S23b-6] (IgG1) to Human SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100µg   $425.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Biotin Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
FITC Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 390 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 565 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 488 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 594 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 680 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
PE, Atto 594 Conjugated
100µg   $405.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 655 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
AP Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
SA Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
PerCP Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 700 Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
RPE Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
APC Conjugated
100µg   $395.00
SHANK2 / SHANK Antibody - Western blot analysis of pan-Shank in rat brain membrane lysates using a 1:1000 dilution of SHANK2 / SHANK antibody.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone S23b-49] (IgG1) to Rat SHANK2 / SHANK
Mouse, Rat, Human
ICC, IF, IHC, IP, WB
Atto 633 Conjugated
100µg   $395.00
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).