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SH3BP1

SH3-domain binding protein 1

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.

Gene Name: SH3-domain binding protein 1
Synonyms: SH3BP1, 3BP-1, ARHGAP43, SH3-domain binding protein 1, SH3 domain binding protein 1, SH3 domain-binding protein 1
Target Sequences: NM_018957 NP_061830.3 Q9Y3L3

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Products
Antibodies (31)
Primary (31)
SH3BP1 (31)
Human (31)
Mouse (4)
Rat (3)
Bovine (3)
Chimpanzee (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
IHC (11)
IHC-P (3)
WB (27)
ELISA (12)
ICC (2)
IF (1)
Peptide-ELISA (1)
rabbit (22)
mouse (8)
goat (1)
Product Group
IHCPlus (1)
IgG (12)
IgG1 (4)
IgG2b (4)
monoclonal mc (8)
polyclonal pc (23)
OTI1C9 (2)
OTI2C7 (2)
OTI2F4 (2)
OTI3G1 (2)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
Carrier-free (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (17)
aa419-446 (7)
C-Terminus (4)
aa125-174 (4)
aa639-701 (1)
aa689-701 (1)
No (31)
SH3BP1 Antibody - Anti-SH3BP1 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
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SH3BP1 Goat anti-Human Polyclonal (aa689-701) Antibody
Human, Monkey
ICC, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
SH3BP1 Antibody - SH3BP1 antibody detects SH3BP1 protein at cytosol on U87 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded U87 xenograft. SH3BP1 antibody dilution:1:500.
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SH3BP1 Rabbit anti-Human Polyclonal (aa639-701) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
SH3BP1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-SH3BP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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SH3BP1 Mouse anti-Human Monoclonal (OTI2F4) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SH3BP1 Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-SH3BP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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SH3BP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2F4) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SH3BP1 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-SH3BP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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SH3BP1 Mouse anti-Human Monoclonal (OTI3G1) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SH3BP1 Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-SH3BP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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SH3BP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI3G1) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SH3BP1 Antibody - Immunohistochemical staining of paraffin-embedded Human thyroid tissue within the normal limits using anti-SH3BP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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SH3BP1 Mouse anti-Human Monoclonal (OTI1C9) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SH3BP1 Antibody - Immunohistochemical staining of paraffin-embedded Human thyroid tissue within the normal limits using anti-SH3BP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:500)
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SH3BP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1C9) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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SH3BP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$351
SH3BP1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SH3BP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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SH3BP1 Mouse anti-Human Monoclonal (OTI2C7) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
SH3BP1 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SH3BP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120°C for 3 min. (1:2000)
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SH3BP1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
SH3BP1 Antibody - Immunohistochemistry Dilution at 1:400 and staining in paraffin-embedded human spleen tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal Goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated Secondary antibody and visualized using an HRP conjugated SP system.
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SH3BP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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SH3BP1 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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SH3BP1 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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SH3BP1 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
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SH3BP1 Rabbit anti-Human Polyclonal (aa419-446) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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SH3BP1 Rabbit anti-Human Polyclonal (aa419-446) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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SH3BP1 Rabbit anti-Human Polyclonal (aa419-446) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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SH3BP1 Rabbit anti-Human Polyclonal (aa419-446) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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SH3BP1 Rabbit anti-Human Polyclonal (aa419-446) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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SH3BP1 Rabbit anti-Human Polyclonal (aa419-446) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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SH3BP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
SH3BP1 Antibody - SH3BP1 antibody Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SH3BP1 Rabbit anti-Human Polyclonal (aa125-174) Antibody
Human
WB
Unconjugated
100 µl/$424
SH3BP1 Antibody - SH3BP1 Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The SH3BP1 antibody detected the SH3BP1 protein (arrow).
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SH3BP1 Rabbit anti-Human Polyclonal (aa419-446) Antibody
Human
WB
Unconjugated
400 µl/$393
SH3BP1 Antibody - Western blot of Human U937. SH3BP1 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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SH3BP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Viewing 1-25 of 31 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).