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SFRP5

secreted frizzled-related protein 5

SARP3 is a frizzled protein that lacks the 7-transmembrane motif used as anchor to the plasma membrane. They modulate Wnt signaling by competing with membrane-bound frizzled receptors for binding secreted Wnt ligands. SARP3 is involved in determining tissue of photoreceptor cells in the retina. It is highly expressed in the retinal pigment epithelium, and moderately expressed in the pancreas.

Gene Name: secreted frizzled-related protein 5
Synonyms: SFRP5, FRP-1b, Frizzled-related protein 5, SFRP-5, SARP-3, Frizzled-related protein 1b, FRP1B, SARP3
Target Sequences: NM_003015 NP_003006.2 Q5T4F7

Publications (1)

1
Secreted frizzled-related protein-5 is epigenetically downregulated and functions as a tumor suppressor in kidney cancer. Kawakami K, Yamamura S, Hirata H, Ueno K, Saini S, Majid S, Tanaka Y, Kawamoto K, Enokida H, Nakagawa M, Dahiya R. International journal of cancer. Journal international du cancer. 2011 128:541-50. (IHC-P; Human) [PubMed:20340127]

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Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
SFRP5 (8)
No (8)
6His, N-terminus (1)
His (5)
Myc-DDK (Flag) (2)
Human (4)
Mouse (2)
Rat (1)
293T Cells (1)
E. coli (6)
HEK 293 Cells (1)
Purified (2)
SFRP5 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
37.2 kDa
1 mg/$1,679; 100 µg/$500; 20 µg/$364
SFRP5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.4 kDa
100 µg/$494
SFRP5 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
SFRP5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
35.4 kDa
20 µg/$150
SFRP5 Protein - Recombinant Secreted Frizzled Related Protein 5 By SDS-PAGE
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E. coli
His
14.8 kDa
10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796
SFRP5 Protein
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E. coli
His
15.5 kDa
10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796
Select
E. coli
His
14.4 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
SFRP5 Protein - Recombinant Secreted Frizzled Related Protein 5 By SDS-PAGE
Select
E. coli
His
14.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).