SF3B130 / SF3B3

splicing factor 3b, subunit 3, 130kDa

SF3B130 / SF3B3 is subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

SF3B130 / SF3B3 (5)

Publications

No (5)

Tag

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Mouse (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human SF3B130 / SF3B3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66491

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

135.4 kDa

Price:

20 µg/$1,107

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Mouse SF3B130 / SF3B3 Protein (Recombinant His, N-Terminal) (aa35-210) - LS-G26174

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

23.1 kDa

Price:

10 µg/$283; 50 µg/$457; 100 µg/$732; 200 µg/$912; 1 mg/$2,032; 500 µg/$1,567; 5 mg/$3,193; 2 mg/$2,219

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Human SF3B130 / SF3B3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77828

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

134.25 kDa

Price:

20 µg/$150

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SF3B130 / SF3B3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114432

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

134.25 kDa

Price:

100 µg/$494

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Human SF3B130 / SF3B3 Protein (Recombinant GST, N-terminus) (aa819-929) - LS-G62004

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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