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Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
Gene Name: | splicing factor 3a, subunit 3, 60kDa |
Synonyms: | SF3A3, PRP9, PRPF9, SAP61, Splicing factor 3A subunit 3, SAP 61, SF3a60 |
Target Sequences: | NM_006802 NP_006793.1 Q12874 |
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