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SETX / Senataxin

senataxin

SETX / Senataxin is a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

Gene Name: senataxin
Synonyms: SETX, AOA2, KIAA0625, ALS4, SCAR1, BA479K20.2, Probable helicase senataxin, SEN1 homolog, Senataxin
Target Sequences: NM_015046 NP_055861.3 Q7Z333

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Proteins (2)
Recombinant (2)
SETX / Senataxin (2)
No (2)
GST, N-terminus (1)
Myc-DDK (Flag), C-terminus (1)
Human (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
SETX / Senataxin Protein
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HEK 293 Cells
Myc-DDK (Flag), C-terminus
57.8 kDa
20 µg/$1,107
SETX / Senataxin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).