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The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene.
Gene Name: | serpin peptidase inhibitor, clade I (pancpin), member 2 |
Synonyms: | SERPINI2, Peptidase inhibitor 14, PI-14, PI14, SERPIN12, TSA2004, MEPI, PANCPIN, Protease inhibitor 14, Serpin I2 |
Target Sequences: | NM_006217 NP_006208.1 O75830 |
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