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SERPINH1 / HSP47

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

SERPINH1 / HSP47 is a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.

Gene Name: serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
Synonyms: SERPINH1, 47 kDa heat shock protein, AsTP3, Colligin, Colligin-1, Collagen-binding protein, Colligin-2, CBP1, HSP47, OI10, Serpin H1, SERPINH2, CBP2, Collagen-binding protein 1, Colligen, gp46, PIG14, PPROM, RA-A47
Target Sequences: NM_001235 NP_001226.2 P50454

Publications (3)

1
Temporal gene expression profiling of the rat knee joint capsule during immobilization-induced joint contractures. Wong K, Sun F, Trudel G, Sebastiani P, Laneuville O. BMC musculoskeletal disorders. 2015 16:125. (ICC; Human, Rat) [Full Text Article] [PubMed:26006773] [PMC:PMC4443538]
2
Functional genomics study of acute heat stress response in the small yellow follicles of layer-type chickens. Cheng CY, Tu WL, Chen CJ, Chan HL, Chen CF, , Chen HH, Tang PC, Lee YP, Chen SE, , Huang SY, ,. Scientific reports. 2018 8:1320. (WB; Human) [Full Text Article] [PubMed:29358656]
3
Proteomic Analysis of Thermal Regulation of Small Yellow Follicles in Broiler-Type Taiwan Country Chickens. Chuen-Yu Cheng, Wei-Lin Tu, Chao-Jung Chen, Hong-Lin Chan, Chih-Feng Chen, Hsin-Hsin Chen, Pin-Chi Tang, Yen-Pai Lee, Shuen-Ei Chen, San-Yuan Huang. The journal of poultry science. 2018 January;55:120-136. [Full Text Article] [PubMed:32055165] [PMC:PMC6756493]

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ELISA Kits (13)
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SERPINH1 / HSP47 (13)
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Cell Lysates (3)
Plasma (9)
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SERPINH1 / HSP47 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
SERPINH1 / HSP47 ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
SERPINH1 / HSP47 ELISA Kit
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Sandwich
96-Well Microplate
Rat
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
SERPINH1 / HSP47 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$669
SERPINH1 / HSP47 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
SERPINH1 / HSP47 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SERPINH1 / HSP47 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.125 - 8 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SERPINH1 / HSP47 ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
SERPINH1 / HSP47 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
SERPINH1 / HSP47 ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
SERPINH1 / HSP47 ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
SERPINH1 / HSP47 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
SERPINH1 / HSP47 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).