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SERPINE2 / Nexin

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

SERPINE2 / Nexin is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.

Gene Name: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
Synonyms: SERPINE2, GDNPF, GDN, PNI, PN1, Protease nexin I, Nexin, Protease nexin 1, Serpin E2, Glia-derived nexin, Peptidase inhibitor 7, PI-7, PI7, PN-1
Target Sequences: A03911 CAA00310.1 P07093

Publications (1)

1
Islet Gene View-a tool to facilitate islet research. Olof Asplund, Petter Storm, Vikash Chandra, Gad Hatem, Emilia Ottosson-Laakso, Dina Mansour-Aly, Ulrika Krus, Hazem Ibrahim, Emma Ahlqvist, Tiinamaija Tuomi, Erik Renström, Olle Korsgren, Nils Wierup, Mark Ibberson, Michele Solimena, Piero Marchetti, Claes Wollheim, Isabella Artner, Hindrik Mulder, Ola Hansson, Timo Otonkoski, Leif Groop, Rashmi B Prasad. Life science alliance. 2022 December;5: [Full Text Article] [PubMed:35948367] [PMC:PMC9366203] Related Antibodies: LS-C173926.

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).