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SERPINB8

serpin peptidase inhibitor, clade B (ovalbumin), member 8

The superfamily of high molecular weight serine proteinase inhibitors (serpins) regulate a diverse set of intracellular and extracellular processes such as complement activation, fibrinolysis, coagulation, cellular differentiation, tumor suppression, apoptosis, and cell migration. Serpins are characterized by well-conserved a tertiary structure that consists of 3 beta sheets and 8 or 9 alpha helices (Huber and Carrell, 1989 [PubMed 2690952]). A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position (summary by Bartuski et al., 1997 [PubMed 9268635]).[supplied by OMIM, Jan 2010]

Gene Name: serpin peptidase inhibitor, clade B (ovalbumin), member 8
Synonyms: SERPINB8, Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, PI8, Serpin B8, PI-8, CAP-2
Target Sequences: NM_002640 NP_002631.3 P50452

☰ Filters
Products
Proteins (13)
Over-Expression Lysate (7)
Recombinant (6)
SERPINB8 (13)
No (13)
6His, N-terminus (1)
8His, N-terminus (1)
GST (1)
His (2)
Myc-DDK (Flag) (8)
Human (9)
Mouse (1)
293T Cells (3)
Baculovirus (1)
E. coli (2)
HEK 293 Cells (6)
Wheat Germ Extract (1)
Purified (3)
Low endotoxin level (1)
SERPINB8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.6 kDa
100 µg/$494
SERPINB8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
42.6 kDa
100 µg/$494
SERPINB8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
27.5 kDa
100 µg/$494
SERPINB8 Protein - 12.5% SDS-PAGE of human SERPINB8 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
52.36 kDa
10 µg/$479; 25 µg/$670
Select
HEK 293 Cells
8His, N-terminus
44.3 kDa
100 µg/$298
SERPINB8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
27.5 kDa
20 µg/$150
SERPINB8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.6 kDa
20 µg/$150
SERPINB8 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.6 kDa
20 µg/$150
SERPINB8 Protein
Select
E. coli
6His, N-terminus
45 kDa
10 µg/$265; 200 µg/$484; 50 µg/$315
Select
Baculovirus
His
Less than 1.0 EU/µg protein (determined by LAL method).
43.6 kDa
100 µg/$843
SERPINB8 Protein - Purified recombinant protein SERPINB8 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42.6 kDa
20 µg/$1,107
SERPINB8 Protein - Purified recombinant protein SERPINB8 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
27.5 kDa
20 µg/$1,107
SERPINB8 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-13 of 13 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).