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SERPINB1

serpin peptidase inhibitor, clade B (ovalbumin), member 1

SERPINB1 is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.

Gene Name: serpin peptidase inhibitor, clade B (ovalbumin), member 1
Synonyms: SERPINB1, Anti-elastase, EI, LEI, Leukocyte elastase inhibitor, Peptidase inhibitor 2, PI-2, MNEI, ELANH2, M/NEI, PI2, Serpin B1
Target Sequences: NM_030666 NP_109591.1 P30740

Publications (2)

1
Circulating SerpinB1 levels and clinical features in patients with type 2 diabetes. Takebayashi K, Hara K, Terasawa T, Naruse R, Suetsugu M, Tsuchiya T, Inukai T. BMJ open diabetes research & care. 2016 November;4:e000274. [Full Text Article] [PubMed:27933185] [PMC:PMC5128937]
2
Association between circulating SerpinB1 levels and insulin sensitivity in Japanese with type 2 diabetes: A single-center, cross-sectional, observational study. Mayu Kyohara, Daisuke Miyashita, Ryota Inoue, Kuniyuki Nishiyama, Takahiro Tsuno, Tomoko Okuyama, Yu Togashi, Yasuo Terauchi, Jun Shirakawa. PloS one. 2022 November;17:e0276915. [Full Text Article] [PubMed:36331940] [PMC:PMC9635728]

☰ Filters
Products
Proteins (13)
Over-Expression Lysate (2)
Recombinant (11)
SERPINB1 (13)
No (13)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His,C-terminus (1)
His-SUMO (1)
His-T7 (3)
Myc-DDK (Flag) (3)
Human (10)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Human Cells (1)
Insect Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (3)
SERPINB1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.6 kDa
100 µg/$494
SERPINB1 Protein - Recombinant Leukocyte Elastase Inhibitor By SDS-PAGE
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E. coli
His-T7
31.1 kDa
50 µg/$442; 10 µg/$281; 200 µg/$882; 100 µg/$705; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
SERPINB1 Protein
Select
E. coli
His-SUMO
58.7 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
SERPINB1 Protein - Recombinant  Leukocyte Elastase Inhibitor By SDS-PAGE
Select
E. coli
His-T7
40.5 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
SERPINB1 Protein - Recombinant  Leukocyte Elastase Inhibitor By SDS-PAGE
Select
E. coli
His-T7
24.8 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
SERPINB1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
43.8kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Select
293T Cells
Myc-DDK (Flag)
42.6 kDa
20 µg/$150
SERPINB1 Protein - Purified recombinant protein SERPINB1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42.6 kDa
20 µg/$1,107
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Insect Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
44 kDa
50 µg/$721
SERPINB1 Protein
Select
E. coli
His, N-Terminal
42.7 kDa
50 µg/$419
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
43.8 kDa
10 µg/$288; 50 µg/$436
SERPINB1 Protein - 12.5% SDS-PAGE of human SERPINB1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
67.43 kDa
10 µg/$479; 25 µg/$670
Viewing 1-13 of 13 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).