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SEPT6 / Septin 6
septin 6
SEPT6 / Septin 6 is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.
| Gene Name: | septin 6 |
| Synonyms: | SEPT6, KIAA0128, RP5-876A24.2, SEP2, Septin 2, Septin 2 homolog, Septin 6, Septin-6 |
| Target Sequences: | NM_015129 BAA09477.1 Q14141 |
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