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SEPT2 / Septin 2

septin 2

Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Gene Name: septin 2
Synonyms: SEPT2, DIFF6, HNedd5, KIAA0158, NEDD5, Septin-2, Septin 2, NEDD-5, PNUTL3
Target Sequences: NM_004404 NP_004395.1 Q15019

☰ Filters
Products
Proteins (19)
Over-Expression Lysate (10)
Recombinant (9)
SEPT2 / Septin 2 (19)
No (19)
6His-SUMO, N-terminus (1)
GST (2)
His (1)
Myc-DDK (Flag) (15)
Human (14)
293T Cells (5)
E. coli (2)
HEK 293 Cells (10)
Wheat Germ Extract (2)
Purified (4)
SEPT2 / Septin 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
41.3 kDa
100 µg/$494
Select
HEK 293 Cells
Myc-DDK (Flag)
41.3 kDa
100 µg/$494
SEPT2 / Septin 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
41.3 kDa
100 µg/$494
Select
HEK 293 Cells
Myc-DDK (Flag)
41.3 kDa
100 µg/$494
SEPT2 / Septin 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
41.3 kDa
100 µg/$494
SEPT2 / Septin 2 Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
SEPT2 / Septin 2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
293T Cells
Myc-DDK (Flag)
41.3 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
41.3 kDa
20 µg/$150
SEPT2 / Septin 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
41.3 kDa
20 µg/$150
SEPT2 / Septin 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
41.3 kDa
20 µg/$150
SEPT2 / Septin 2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
41.3 kDa
20 µg/$150
SEPT2 / Septin 2 Protein - Purified recombinant protein SEPT2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
41.3 kDa
20 µg/$1,107
SEPT2 / Septin 2 Protein - Purified recombinant protein SEPT2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
41.3 kDa
20 µg/$1,107
SEPT2 / Septin 2 Protein - Purified recombinant protein SEPT2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
41.3 kDa
20 µg/$1,107
SEPT2 / Septin 2 Protein - Purified recombinant protein SEPT3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
40.5 kDa
20 µg/$1,107
SEPT2 / Septin 2 Protein - Purified recombinant protein SEPT3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
39.9 kDa
20 µg/$1,107
SEPT2 / Septin 2 Protein - 12.5% SDS-PAGE of human SEPT2 stained with Coomassie Blue
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Wheat Germ Extract
GST
66.33 kDa
10 µg/$479; 25 µg/$670
SEPT2 / Septin 2 Protein - 12.5% SDS-PAGE of human SEPT2 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
65.23 kDa
10 µg/$479; 25 µg/$670
Viewing 1-19 of 19 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).