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Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.
Gene Name: | SUMO/sentrin specific peptidase family member 8 |
Synonyms: | SENP8, DEN1, Deneddylase-1, FKSG8, HsT17512, PRSC2, NEDD8-specific protease 1, Sentrin-specific protease 8, Deneddylase 1, NEDP1, Protease, cysteine 2 |
Target Sequences: | NM_145204 |
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