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SEMA4C / Semaphorin 4C

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C

Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration By similarity. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.

Gene Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Synonyms: SEMA4C, M-Sema F, SEMAF, SEMACL1, Semaphorin-4C, KIAA1739, M-SEMA-F, SEMAI
Target Sequences: NM_017789 NP_060259.4 Q9C0C4

Publications (1)

1
Plexin-B2 promotes invasive growth of malignant glioma. Le AP, Huang Y, Pingle SC, Kesari S, Wang H, Yong RL, Zou H, Friedel RH. Oncotarget. 2015 6:7293-304. (WB; Human) [Full Text Article] [PubMed:25762646] [PMC:PMC4466685] Related Antibodies: LS-C168955.

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
SEMA4C / Semaphorin 4C (4)
No (4)
Fc, C-terminus (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
Mouse (1)
293T Cells (1)
HEK 293 Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Low endotoxin level (1)
SEMA4C / Semaphorin 4C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.4 kDa
20 µg/$215
SEMA4C / Semaphorin 4C Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
SEMA4C / Semaphorin 4C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.4 kDa
100 µg/$710
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Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
99.3 kDa
10 µg/$317; 50 µg/$524
Viewing 1-4 of 4 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).