SEMA4A / Semaphorin 4A

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A

SEMA4A / Semaphorin 4A is a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

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Products

Proteins (12)

Type

Over-Expression Lysate (4)

Recombinant (8)

Target

SEMA4A / Semaphorin 4A (12)

Publications

No (12)

Tag

6His, C-terminus (2)

Fc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His,C-terminus (1)

Human IgG1 Fc (1)

Myc-DDK (Flag) (5)

Species

Human (7)

Mouse (3)

Source

293T Cells (2)

CHO Cells (1)

HEK 293 Cells (5)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (5)

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Mouse SEMA4A / Semaphorin 4A Protein (Recombinant Human IgG1 Fc) (aa1-676) - LS-G4136

Source:

CHO Cells

Tag:

Human IgG1 Fc

Endotoxin Level:

Less than 0.06 EU/µg protein (determined by LAL method).

Price:

100 µg/$512

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Mouse SEMA4A / Semaphorin 4A Protein (Recombinant 6His, C-terminus) (Thr33-His682) - LS-G39931

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

72.7kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353

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Human SEMA4A / Semaphorin 4A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91621

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.6 kDa

Price:

20 µg/$150

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Human SEMA4A / Semaphorin 4A Protein (Recombinant GST, N-terminus) (aa33-132) - LS-G63080

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human SEMA4A / Semaphorin 4A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91622

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.4 kDa

Price:

20 µg/$150

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SEMA4A / Semaphorin 4A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101806

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.4 kDa

Price:

100 µg/$494

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SEMA4A / Semaphorin 4A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G131062

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

69.6 kDa

Price:

100 µg/$494

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Human SEMA4A / Semaphorin 4A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72182

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

83.4 kDa

Price:

20 µg/$1,107

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Human SEMA4A / Semaphorin 4A Protein (Recombinant His,C-terminus) (Met1-His683) - LS-G138017

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

73.4 kDa

Price:

100 µg/$721

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Human SEMA4A / Semaphorin 4A Protein (Recombinant Fc, C-terminus) (Met1-His683) - LS-G138018

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

99 kDa

Price:

100 µg/$721

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Human SEMA4A / Semaphorin 4A Protein (Recombinant GST) (Full Length) - LS-G34956

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

110 kDa

Price:

2 µg/$439

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Mouse SEMA4A / Semaphorin 4A Protein (Recombinant 6His, C-terminus) (Thr33-His682) - LS-G140652

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

72.7 kDa

Price:

10 µg/$317; 50 µg/$524

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