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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
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SELP / P-Selectin / CD62P

selectin P (granule membrane protein 140kDa, antigen CD62)

SELP encodes a 140 kD protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

Gene Name: selectin P (granule membrane protein 140kDa, antigen CD62)
Synonyms: SELP, CD62P, CD62, GMP-140, GMRP, Granule membrane protein 140, LECAM3, P-selectin, PSEL, CD62P antigen, GMP140, Granulocyte membrane protein, GRMP, PADGEM
Target Sequences: NM_003005 NP_002996.2

Publications (2)

1
Targeting P-selectin blocks neuroblastoma growth. Nolo R, Herbrich S, Rao A, Zweidler-McKay P, Kannan S, Gopalakrishnan V, ,. Oncotarget. 2017 8:86657-86670. (IP; Human) [Full Text Article] [PubMed:29156825] Related Antibodies: LS-B3656.
2
Chronic Embolic Pulmonary Hypertension Caused by Pulmonary Embolism and Vascular Endothelial Growth Factor Inhibition. Neto-Neves EM, Brown MB, Zaretskaia MV, Rezania S, Goodwill AG, McCarthy BP, Persohn SA, Territo PR, Kline JA. The American journal of pathology. 2017 April;187:700-712. [Full Text Article] [PubMed:28183533] [PMC:PMC5397717]

Viewing 1-25 of 110 items
SELP / P-Selectin / CD62P Antibody - Anti-CD62P antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Mouse Monoclonal [clone Psel.KO.2.5] (IgG1) to Human SELP / P-Selectin / CD62P
Human
Flo, IHC, IHC-P, IP
Unconjugated
0.05mg   1mg/ml   $425.00
SELP / P-Selectin / CD62P Antibody - Anti-CD62P antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Select
Rabbit Polyclonal to Mouse SELP / P-Selectin / CD62P
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µg   0.5mg/ml   $485.00
SELP / P-Selectin / CD62P Antibody - Human Tonsil, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Mouse Monoclonal [clone AK-6] (IgG1) to Human SELP / P-Selectin / CD62P
Human
Flo, IF, IHC-Fr, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
SELP / P-Selectin / CD62P Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human SELP / P-Selectin / CD62P
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $425.00
SELP / P-Selectin / CD62P Antibody - ABCG2 antibody, PB9364, IHC-paraffin: Human Lung Cancer Tissue.
Select
Rabbit Polyclonal to Human SELP / P-Selectin / CD62P
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µg   0.5mg/ml   $355.00
Select
Mouse Monoclonal [clone CRC81] (IgG1,k) to Human SELP / P-Selectin / CD62P
Human
IF
Unconjugated
1ml   $605.00
Select
Mouse Monoclonal (IgG1) to Human SELP / P-Selectin / CD62P
Pig, Human
Flo, IP
PE Conjugated
100µl   1mg/ml   $815.00
Select
Mouse Monoclonal [clone Psel.KO.2.12] (IgG1) to Human SELP / P-Selectin / CD62P
Human
Flo
RPE Conjugated
100tst   $415.00
SELP / P-Selectin / CD62P Antibody - Flow cytometry of thrombin activated human peripheral blood platelets with Mouse anti-Human CD62P:RPE This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Mouse Monoclonal [clone Psel.KO.2.5] (IgG1) to Human SELP / P-Selectin / CD62P
Human
Flo
RPE Conjugated
100tst   $415.00
SELP / P-Selectin / CD62P Antibody - Western Blot; Sample: Recombinant SELP, Human.
Select
Rabbit Polyclonal to Human SELP / P-Selectin / CD62P
Human
WB
Unconjugated
100µl   0.5mg/ml   $225.00; 200µl   0.5mg/ml   $245.00; 500µl   0.5mg/ml   $335.00; 1ml   0.5mg/ml   $385.00
SELP / P-Selectin / CD62P Antibody - Western Blot; Sample: Recombinant SELP, Human.
Select
Rabbit Polyclonal to Human SELP / P-Selectin / CD62P
Human
WB
Biotin Conjugated
200µl   0.5mg/ml   $255.00; 500µl   0.5mg/ml   $355.00; 1ml   0.5mg/ml   $405.00
Select
Mouse Monoclonal [clone CRC81] (IgG1,k) to Human SELP / P-Selectin / CD62P
Human
IF
Unconjugated, Concentrated
1ml   $395.00
Select
Mouse Monoclonal [clone Psel.KO.2.7] (IgG1) to Human SELP / P-Selectin / CD62P
Human
Flo
RPE Conjugated
100tst   $415.00
Select
Mouse Monoclonal [clone AK4] (IgG1) to Human SELP / P-Selectin / CD62P
Human, Non-Human Primates
Flo, Func, ICC, IP, WB
Unconjugated, Low Endotoxin
0.1mg   1mg/ml   $255.00
Select
Mouse Monoclonal [clone Psel.KO.2.12] (IgG1) to Human SELP / P-Selectin / CD62P
Human
Flo, IHC, IHC-Fr, IP
Unconjugated
25µg   $225.00; 0.2mg   1mg/ml   $395.00
Select
Mouse Monoclonal [clone Psel.KO.2.7] (IgG1) to Human SELP / P-Selectin / CD62P
Human
Flo, IHC-Fr, IP
Unconjugated
25µg   $225.00; 0.2mg   1mg/ml   $395.00
Select
Rabbit Monoclonal [clone 001] (IgG) to Mouse SELP / P-Selectin / CD62P
Mouse
ELISA
Unconjugated, Preservative Free
50µl   $245.00; 100µl   $305.00
SELP / P-Selectin / CD62P Antibody - Western blot - Anti-CD62P Picoband antibody
Select
Rabbit Polyclonal to Mouse SELP / P-Selectin / CD62P
Mouse
ELISA, Flo, ICC, IHC, WB
Unconjugated
100µg   $355.00
SELP / P-Selectin / CD62P Antibody - Western blot of recombinant SELP / P-Selectin / CD62P.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse SELP / P-Selectin / CD62P
Mouse
WB
Unconjugated
100µl   0.5mg/ml   $215.00; 200µl   0.5mg/ml   $245.00; 500µl   0.5mg/ml   $325.00; 1ml   0.5mg/ml   $375.00
SELP / P-Selectin / CD62P Antibody - 5-10ug/ml, non-reducing and non-heating conditions.
Select
Mouse Monoclonal (IgG1) to Human SELP / P-Selectin / CD62P
Human
ELISA, Flo, IHC, IHC-Fr, WB
Unconjugated
100µg   $545.00
Select
Mouse Monoclonal [clone AK4] (IgG1) to Human SELP / P-Selectin / CD62P
Human, Non-Human Primate
Flo, Func, ICC, IP, WB
Unconjugated
100µg   $295.00
Select
Mouse Monoclonal [clone AK4] (IgG1) to Human SELP / P-Selectin / CD62P
Human, Non-Human Primates
Flo, Func, ICC, IP, WB
Unconjugated
0.1mg   1mg/ml   $255.00
Select
Mouse Monoclonal (IgG1) to Human SELP / P-Selectin / CD62P
Human
ELISA, IHC, IP, WB
Unconjugated
100µg   $465.00
SELP / P-Selectin / CD62P Antibody - Western blot of recombinant SELP / P-Selectin / CD62P.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Rat SELP / P-Selectin / CD62P
Rat
WB
Biotin Conjugated
200µl   0.5mg/ml   $295.00; 500µl   0.5mg/ml   $425.00; 1ml   0.5mg/ml   $495.00
Select
Mouse Monoclonal [clone AK4] (IgG1) to Human SELP / P-Selectin / CD62P
Human, Non-Human Primates
Flo, Func, ICC, IP, WB
FITC Conjugated
100tst   $290.00

Viewing 1-25 of 110 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).