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SCN11A / Nav1.9

sodium channel, voltage-gated, type XI, alpha subunit

Scn12a encodes the alpha subunit of the type XII voltage-gated sodium channel. These channels, composed of one alpha and one or two beta subunits, mediate changes in cell permeability to sodium ions that are essential for the generation of action potentials. The alpha subunit alone has been shown to generate a functional channel in vitro, but it's kinetic properties are modulated by beta subunits. Scn12a, which produces produces a persistent, tetrodotoxin-resistant current with wide overlap between activation and steady-state inactivation, has been implicated in nociceptive transmission. At least two alternative splicing variants have been reported. Scn12a is considered an attractive target for pain treatment.

Gene Name: sodium channel, voltage-gated, type XI, alpha subunit
Family/Subfamily: Ion Channel , Sodium channel - voltage-gated
Synonyms: SCN11A, HNaN, NaT, NAV1.9, PN5, SNS-2, SNS2, NaN, SCN12A
Target Sequences: NM_014139 NP_054858.2 Q9UI33

☰ Filters
Antibodies (10)
Proteins (1)
Primary (10)
Recombinant (1)
SCN11A / Nav1.9 (11)
Human (9)
Mouse (3)
Rat (3)
IHC (5)
IHC-P (1)
WB (4)
ELISA (4)
IF (1)
Peptide-ELISA (1)
rabbit (9)
rabbit-new zealand white (1)
IgG (7)
polyclonal pc (10)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (7)
No (11)
GST, N-terminus (1)
Human (1)
Wheat Germ Extract (1)
Select
SCN11A / Nav1.9 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
SCN11A / Nav1.9 Antibody - Western blot analysis SCN11A using 293 whole cells lysates
Select
SCN11A / Nav1.9 Rabbit anti-Human Polyclonal Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SCN11A / Nav1.9 Antibody - Immunohistochemistry image at a dilution of 1:500 and staining in paraffin-embedded human cervical cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Select
SCN11A / Nav1.9 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
SCN11A / Nav1.9 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
SCN11A / Nav1.9 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
SCN11A / Nav1.9 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
Select
SCN11A / Nav1.9 Rabbit-New Zealand White anti-Mouse Polyclonal Antibody
Mouse, Rat
IHC, WB
Unconjugated
100 µl/$393
SCN11A / Nav1.9 Antibody - Immunohistochemistry of paraffin-embedded Human breast cancer using SCN11A Polyclonal Antibody at dilution of 1:40.
Select
SCN11A / Nav1.9 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SCN11A / Nav1.9 Antibody - Immunohistochemistry of paraffin-embedded Human ovarian cancer using SCN11A Polyclonal Antibody at dilution of 1:50.
Select
SCN11A / Nav1.9 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
SCN11A / Nav1.9 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
SCN11A / Nav1.9 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-11 of 11 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).