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SCIN

scinderin

Ca2+-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca2+. Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes.

Gene Name: scinderin
Synonyms: SCIN, Adseverin, KIAA1905, Scinderin
Target Sequences: NM_001112706 NP_001106177.1 Q9Y6U3

Publications (1)

1
Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides. Michel Neidhart, Agnieszka Pajak, Katerina Laskari, Niels P Riksen , Leo A B Joosten , Mihai G Netea , Esther Lutgens , Eric S G Stroes, Adrian Ciurea, Oliver Distler, Mariam Grigorian, Emmanuel Karouzakis. Frontiers in immunology. 2019 Apr;10:791. [Full Text Article] [PubMed:31037071] [PMC:PMC6476283] Related Antibodies: LS-C499726.

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
SCIN (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
SCIN Protein - 12.5% SDS-PAGE of human SCIN stained with Coomassie Blue
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Wheat Germ Extract
GST
79.2 kDa
10 µg/$479; 25 µg/$670
SCIN Protein - Purified recombinant protein SCIN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
52.6 kDa
20 µg/$1,107
SCIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
52.6 kDa
100 µg/$494
SCIN Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
52.6 kDa
20 µg/$150
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).