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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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SCIN
scinderin
Ca2+-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca2+. Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes.
| Gene Name: | scinderin |
| Synonyms: | SCIN, Adseverin, KIAA1905, Scinderin |
| Target Sequences: | NM_001112706 NP_001106177.1 Q9Y6U3 |
Publications (1)
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