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SBDS

Shwachman-Bodian-Diamond syndrome

Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

Gene Name: Shwachman-Bodian-Diamond syndrome
Synonyms: SBDS, CGI-97, SWDS
Target Sequences: NM_016038 NP_057122.2 Q9Y3A5

Filtered By: None
Type
Over-Expression Lysate (2)
Recombinant (4)
Target
sbds (8)
Tag
His (2)
Myc + DDK (3)
Species
E. coli (2)
Human (5)
Source
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Purification
Purified (5)
Showing 1-8 out of 8 results
SBDS Protein (Over-Expression Lysate Myc + DDK) - LS-G112907
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

HEK 293 Cells
302 AA
Myc + DDK
No
No known endotoxin level
28.6 kDa
Human SBDS Protein (Over-Expression Lysate Myc + DDK) - LS-G87199
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

293T Cells
302 AA
Myc + DDK
No
No known endotoxin level
28.6 kDa
Human SBDS Protein (Recombinant His) - LS-G984
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

E. coli
270 AA
His
No
No known endotoxin level
Human SBDS Protein (Recombinant Myc + DDK) - LS-G70483

HEK 293 Cells
302 AA
Myc + DDK
No
No known endotoxin level
28.6 kDa
E. coli SBDS Protein (Met1-Glu250) - LS-G49212

None
No
No known endotoxin level
E. coli SBDS Protein (Met1-Glu250) - LS-G50599

None
No
No known endotoxin level
Human SBDS Protein (Recombinant His) - LS-G19675

E. coli
His
No
No known endotoxin level
30.9 kDa
Human SBDS Protein (Recombinant) - LS-G45647

E. coli
232 AA
None
No
No known endotoxin level

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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