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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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SBDS

Shwachman-Bodian-Diamond syndrome

Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

Gene Name: Shwachman-Bodian-Diamond syndrome
Synonyms: SBDS, CGI-97, SWDS
Target Sequences: NM_016038 NP_057122.2 Q9Y3A5

Filtered By: None
Type
Over-Expression Lysate (2)
Recombinant (4)
Target
sbds (6)
Tag
His (2)
Myc + DDK (3)
Species
Human (5)
Source
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Purification
Purified (3)
Showing 1-6 of 6 results

Human SBDS Protein (Recombinant Myc + DDK) - LS-G70483
HEK 293 Cells
302 AA
Myc + DDK
No
No known endotoxin level
28.6 kDa
20µg  $815.00
Purified recombinant protein SBDS was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Purified recombinant protein SBDS was analyzed by SDS-PAGE gel and Coomassie Blue Staining

SBDS Protein (Over-Expression Lysate Myc + DDK) - LS-G112907
HEK 293 Cells
302 AA
Myc + DDK
No
No known endotoxin level
28.6 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human SBDS Protein (Over-Expression Lysate Myc + DDK) - LS-G87199
293T Cells
302 AA
Myc + DDK
No
No known endotoxin level
28.6 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human SBDS Protein (Recombinant His) - LS-G19675
E. coli
His
No
No known endotoxin level
30.9 kDa
5µg  $195.00; 20µg  $255.00; 1mg  $2,850.00

Human SBDS Protein (Recombinant His) - LS-G984
E. coli
270 AA
His
No
No known endotoxin level
500µg  $680.00; 100µg  $315.00
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image
Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis Image

Human SBDS Protein (Recombinant) - LS-G45647
E. coli
232 AA
None
No
No known endotoxin level
5µg  $255.00
Showing 1-6 of 6 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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