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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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SAT1 / SAT
spermidine/spermine N1-acetyltransferase 1
Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine.
| Gene Name: | spermidine/spermine N1-acetyltransferase 1 |
| Synonyms: | SAT1, DC21, Diamine acetyltransferase 1, Diamine acetyltransferase, Diamine N-acetyltransferase 1, KFSD, KFSDX, Putrescine acetyltransferase, SAT, SSAT, SSAT-1 |
| Target Sequences: | NM_002970 NP_002961.1 P21673 |
Publications (1)
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