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Central scaffolding component of the centrioles ensuring their 9-fold symmetry. Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells. Overexpression results in excess foci-bearing centriolar markers.
Gene Name: | spindle assembly 6 homolog (C. elegans) |
Synonyms: | SASS6, SAS6, HsSAS-6, SAS-6 |
Target Sequences: | Q6UVJ0 Q6UVJ0 |
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