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S100A7 / Psoriasin
S100 calcium binding protein A7
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
| Gene Name: | S100 calcium binding protein A7 |
| Synonyms: | S100A7, PSOR1, Psoriasin, Protein S100-A7, Psoriasin 1, S100A7c |
| Target Sequences: | NM_002963 NP_002954.2 P31151 |
Publications (1)
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