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S100A2 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.
Gene Name: | S100 calcium binding protein A2 |
Synonyms: | S100A2, CAN19, Protein S-100L, Protein S100-A2, S100L |
Target Sequences: | NM_005978 NP_005969.1 P29034 |
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