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RUNX3

runt-related transcription factor 3

RUNX3 is a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: runt-related transcription factor 3
Synonyms: RUNX3, Acute myeloid leukemia gene 2, CBF-alpha-3, PEA2 alpha C, PEBP2 alpha C, PEBP2-alpha C, PEBP2A3, PEBP2aC, AML2, Oncogene AML-2, CBFA3, PEA2-alpha C, Transcription factor AML2
Target Sequences: NM_004350 NP_004341.1 Q13761

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
RUNX3 (7)
No (7)
10His, N-terminus + Myc, C-terminus (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
His-T7, N-terminus (1)
Myc-DDK (Flag) (2)
Human (5)
Mouse (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
RUNX3 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
10His, N-terminus + Myc, C-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RUNX3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.7 kDa
100 µg/$494
RUNX3 Protein
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E. coli
His
50 µg/$357; 250 µg/$692; 10 µg/$272; 20 µg/$317; 100 µg/$452; 500 µg/$1,147
RUNX3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
45.7 kDa
20 µg/$150
RUNX3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RUNX3 Protein - Recombinant Runt Related Transcription Factor 3 (RUNX3) by SDS-PAGE
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E. coli
His-T7, N-terminus
30.7kDa
10 µg/$243; 50 µg/$291; 200 µg/$402; 100 µg/$339; 1 mg/$1,156; 500 µg/$802; 5 mg/$1,982; 2 mg/$1,298
RUNX3 Protein
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E. coli
His, N-Terminal
45.7 kDa
50 µg/$419
Viewing 1-7 of 7 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).