RSPO1 / RSPO

R-spondin 1

Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination.

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Products

Proteins (14)

Type

Over-Expression Lysate (2)

Recombinant (12)

Target

RSPO1 / RSPO (14)

Publications

No (14)

Tag

6His, C-terminus (2)

His (2)

His, N-Terminal (2)

His,C-terminus (2)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (8)

Mouse (3)

Rat (2)

Source

293T Cells (1)

CHO Cells (3)

E. coli (4)

HEK 293 Cells (2)

Human Cells (2)

Mammalian Cells (2)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (2)

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Mouse RSPO1 / RSPO Protein (Recombinant His) (aa21-135) - LS-G16201

Source:

E. coli

Tag:

His

Molecular Weight:

14.2 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Rat RSPO1 / RSPO Protein (Recombinant His, N-Terminal) (Ala136-Thr262) - LS-G16203

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

15.6 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209

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Mouse RSPO1 / RSPO Protein (Recombinant) - LS-G133824

Source:

CHO Cells

Tag:

None

Molecular Weight:

27.1 kDa or 40.0 kDa

Price:

20 µg/$349; 5 µg/$268

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Human RSPO1 / RSPO Protein (Recombinant His,C-terminus) (Met1-Ala146) - LS-G139029

Source:

HEK 293 Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

14 kDa

Price:

100 µg/$815; 1 mg/$4,305

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RSPO1 / RSPO Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120558

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.8 kDa

Price:

100 µg/$494

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Rat RSPO1 / RSPO Protein (Recombinant His, N-Terminal) (Ser21-Ala135) - LS-G16207

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

14.2 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209

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Human RSPO1 / RSPO Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93847

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.8 kDa

Price:

20 µg/$150

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Human RSPO1 / RSPO Protein (Recombinant His) (Met1-Ala263) - LS-G98652

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

28.2 kDa

Price:

100 µg/$962

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Human RSPO1 / RSPO Protein (Recombinant) - LS-G99

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

26.7 kDa

Price:

5 µg/$268; 20 µg/$349

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Human RSPO1 / RSPO Protein (Recombinant) - LS-G145596

Source:

Human Cells

Tag:

None

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

35 kDa

Price:

10 µg/$364; 1 mg/$3,412; 50 µg/$733

Select

Mouse RSPO1 / RSPO Protein (Recombinant His,C-terminus) (Met1-Gln265) - LS-G138233

Source:

CHO Cells

Tag:

His,C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

28.5 kDa

Price:

100 µg/$741

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Human RSPO1 / RSPO Protein (Recombinant 6His, C-terminus) - LS-G136821

Source:

Mammalian Cells

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

26.6 kDa

Price:

50 µg/$516; 10 µg/$313; 1 mg/$2,837; 500 µg/$1,987

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Human RSPO1 / RSPO Protein (Recombinant 6His, C-terminus) (Arg31-Ala263) - LS-G139694

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

26.6 kDa

Price:

10 µg/$288; 50 µg/$436

Select

Human RSPO1 / RSPO Protein (Recombinant His-T7) (aa21-135) - LS-G16205

Source:

E. coli

Tag:

His-T7

Molecular Weight:

16.5 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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