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RPS6KB2 / S6K2 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Gene Name: | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
Family/Subfamily: | Protein Kinase , P70 RSK |
Synonyms: | RPS6KB2, KLS, p70 S6K-beta, p70-beta-1, p70-beta-2, p70S6Kb, p70 ribosomal S6 kinase beta, p70(S6K)-beta, p70-beta, S6K-beta, S6K-beta-2, S6K-beta2, SRK, p70-S6K 2, S6 kinase-related kinase, p70 S6 kinase beta, p70 S6KB, p70S6K2, S6 kinase 2, S6K2, STK14B |
Target Sequences: | NM_003952 NP_003943.2 Q9UBS0 |
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