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This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome.
Gene Name: | ribophorin I |
Synonyms: | RPN1, Ribophorin-1, RPN-I, OST1, RBPH1, Ribophorin I |
Target Sequences: | NM_002950 NP_002941.1 |
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