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RPL5 / Ribosomal Protein L5

ribosomal protein L5

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L18P family of ribosomal proteins. It is located in the cytoplasm. The protein binds 5S rRNA to form a stable complex called the 5S ribonucleoprotein particle (RNP), which is necessary for the transport of nonribosome-associated cytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. The protein interacts specifically with the beta subunit of casein kinase II. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. This gene is co-transcribed with the small nucleolar RNA gene U21, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Gene Name: ribosomal protein L5
Synonyms: RPL5, 60S ribosomal protein L5, DBA6, L5, Ribosomal protein L5, MSTP030
Target Sequences: NM_000969 NP_000960.2 P46777

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
RPL5 / Ribosomal Protein L5 (6)
No (6)
GST (2)
GST, N-terminus + His, C-terminus (1)
His (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (2)
RPL5 / Ribosomal Protein L5 Protein
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E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
RPL5 / Ribosomal Protein L5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34.2 kDa
100 µg/$494
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E. coli
GST
61.6 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
RPL5 / Ribosomal Protein L5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34.2 kDa
20 µg/$150
RPL5 / Ribosomal Protein L5 Protein
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E. coli
GST, N-terminus + His, C-terminus
62.2 kDa
50 µg/$419
RPL5 / Ribosomal Protein L5 Protein - 12.5% SDS-PAGE of human RPL5 stained with Coomassie Blue
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Wheat Germ Extract
GST
36.85 kDa
10 µg/$479; 25 µg/$670
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).