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ROX / MNT

MAX network transcriptional repressor

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.

Gene Name: MAX network transcriptional repressor
Synonyms: MNT, BHLHd3, Max-binding protein MNT, MAX binding protein, Max-interacting protein, MNT, MAX dimerization protein, Protein ROX, Myc antagonist MNT, MAD6, MXD6, ROX
Target Sequences: NM_020310 NP_064706.1

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Proteins (1)
Recombinant (1)
ROX / MNT (1)
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GST, N-terminus (1)
Human (1)
Wheat Germ Extract (1)
ROX / MNT Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).