RNF170

ring finger protein 170

RNF170 is a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene.

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Proteins (2)

Type

Recombinant (2)

Target

RNF170 (2)

Publications

No (2)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

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Human RNF170 Protein (Recombinant GST) (Full Length) - LS-G35530

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

48.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human RNF170 Protein (Recombinant GST, N-terminus) (aa121-193) - LS-G63282

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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