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RNF125 is a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway.
Gene Name: | ring finger protein 125, E3 ubiquitin protein ligase |
Synonyms: | RNF125, RING finger protein 125, TRAC-1, TRAC1 |
Target Sequences: | NM_017831 NP_060301.2 Q96EQ8 |
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