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Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
Gene Name: | ring finger protein 123 |
Synonyms: | RNF123, FP1477, KPC1, Ring finger protein 123, Ubiquitin ligase |
Target Sequences: | NM_022064 NP_071347.2 Q5XPI4 |
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