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Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
Gene Name: | Ribonuclease H2, Subunit B |
Synonyms: | RNASEH2B, AGS2, Aicardi-Goutieres syndrome 2, DLEU8, Ribonuclease H2 subunit B, Ribonuclease H2, subunit B, RNase H2 subunit B, Ribonuclease HI subunit B |
Target Sequences: | NM_024570 NP_078846.2 Q5TBB1 |
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