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Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Gene Name: | ribonuclease, RNase A family, 3 |
Synonyms: | RNASE3, ECP, Ribonuclease 3, RNase 3, Cytotoxic ribonuclease, Eosinophil cationic protein, RNS3 |
Target Sequences: | NM_002935 NP_002926.2 P12724 |
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