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RIP1 / RALBP1

ralA binding protein 1

Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.

Gene Name: ralA binding protein 1
Synonyms: RALBP1, 76 kDa Ral-interacting protein, DNP-SG ATPase, Ral-interacting protein 1, RalA-binding protein 1, RIP1, Rlip76 protein, RIP, RLIP1, RalA binding protein 1, RLIP76
Target Sequences: NM_006788 NP_006779.1 Q15311

Publications (1)

1
Medium-Chain Triglycerides Attenuate Liver Injury in Lipopolysaccharide-Challenged Pigs by Inhibiting Necroptotic and Inflammatory Signaling Pathways. Zhang L, Wang X, Chen S, Wang S, Tu Z, Zhang G, Zhu H, Li X, Xiong J, Liu Y. International journal of molecular sciences. 2018 November;19:pii E3697. [Full Text Article] [PubMed:30469452] [PMC:PMC6274951] Related Antibodies: LS-B8214.

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Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
RIP1 / RALBP1 (9)
No (9)
GST (1)
His (5)
Myc-DDK (Flag) (3)
Human (5)
Mouse (2)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
RIP1 / RALBP1 Protein - 12.5% SDS-PAGE of human RALBP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
97.79 kDa
2 µg/$439
RIP1 / RALBP1 Protein - Purified recombinant protein RALBP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
75.9 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
75.9 kDa
20 µg/$150
RIP1 / RALBP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
75.9 kDa
100 µg/$494
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E. coli
His
12.1 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
RIP1 / RALBP1 Protein - Recombinant RalA Binding Protein 1 By SDS-PAGE
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E. coli
His
23.3 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,889
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E. coli
His
13.0 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
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E. coli
His
23.2 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
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E. coli
His
13.2 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).