RHBDD1

rhomboid domain containing 1

Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions. Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors. Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins. Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing. Involved in the regulation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway. Involved in the regulation of apoptosis; modulates BIK-mediated apoptotic activity. Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity in spermatogonia.

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Proteins (5)

Type

Over-Expression Lysate (4)

Recombinant (1)

Target

RHBDD1 (5)

Publications

No (5)

Tag

Myc-DDK (Flag) (5)

Species

Human (3)

Source

293T Cells (2)

HEK 293 Cells (3)

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RHBDD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129608

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.3 kDa

Price:

100 µg/$494

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RHBDD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108916

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.6 kDa

Price:

100 µg/$494

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Human RHBDD1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69062

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.6 kDa

Price:

20 µg/$1,107

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Human RHBDD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83774

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.6 kDa

Price:

20 µg/$150

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Human RHBDD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83773

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.3 kDa

Price:

20 µg/$150

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