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RGS4

regulator of G-protein signaling 4

Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene.

Gene Name: regulator of G-protein signaling 4
Family/Subfamily: Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling
Synonyms: RGS4, Schizophrenia disorder 9, RGP4, SCZD9
Target Sequences: NM_005613 NP_005604.1 P49798

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Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
RGS4 (8)
No (8)
GST (1)
His (1)
His-T7 (1)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (2)
RGS4 Protein - 12.5% SDS-PAGE of human RGS4 stained with Coomassie Blue
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Wheat Germ Extract
GST
48.29 kDa
10 µg/$479; 25 µg/$670
RGS4 Protein - Purified recombinant protein RGS4 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.1 kDa
20 µg/$1,107
RGS4 Protein
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E. coli
His
50 µg/$361; 250 µg/$708; 10 µg/$274; 20 µg/$320; 100 µg/$458; 500 µg/$1,166
RGS4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.1 kDa
100 µg/$494
RGS4 Protein - Recombinant Regulator Of G Protein Signaling 4 By SDS-PAGE
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E. coli
His-T7
22.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
RGS4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
33.7 kDa
100 µg/$494
RGS4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
33.7 kDa
20 µg/$150
RGS4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
23.1 kDa
20 µg/$150
Viewing 1-8 of 8 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).