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RGS17 / RGSZ2

regulator of G-protein signaling 17

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins.

Gene Name: regulator of G-protein signaling 17
Family/Subfamily: Regulator of G-protein signalling , not assigned-Regulator of G-protein signalling
Synonyms: RGS17, HRGS17, RGS-17, RGSZ2
Target Sequences: NM_012419 NP_036551.3 Q9UGC6

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
RGS17 / RGSZ2 (6)
No (6)
GST (1)
GST, N-terminus (1)
His (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
RGS17 / RGSZ2 Protein - 12.5% SDS-PAGE of human RGS17 stained with Coomassie Blue
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Wheat Germ Extract
GST
48.73 kDa
10 µg/$479; 25 µg/$670
RGS17 / RGSZ2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
24.2 kDa
20 µg/$150
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E. coli
His, N-Terminal
24.4 kDa
50 µg/$419
RGS17 / RGSZ2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
RGS17 / RGSZ2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
24.2 kDa
100 µg/$494
RGS17 / RGSZ2 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).