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RFC1 / RFC
replication factor C (activator 1) 1, 145kDa
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA.
| Gene Name: | replication factor C (activator 1) 1, 145kDa |
| Synonyms: | RFC1, A1 140 kDa subunit, Activator 1 large subunit, Activator 1 140 kDa subunit, Activator 1 subunit 1, DNA-binding protein PO-GA, Replication factor C subunit 1, RF-C 140 kDa subunit, MHC binding factor, beta, PO-GA, MHCBFB, RECC1, Replication factor C1, RFC, RFC140 |
| Target Sequences: | NM_002913 NP_002904.3 P35251 |
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