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REPS2 is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | RALBP1 Associated Eps Domain Containing 2 |
Synonyms: | REPS2, Partner of RalBP1, POB1, RalBP1-interacting protein 2 |
Target Sequences: | NM_004726 NP_004717.2 Q8NFH8 |
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