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RELN / Reelin

reelin

Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.

Gene Name: reelin
Synonyms: RELN, LIS2, PRO1598, Reelin, RL
Target Sequences: NM_005045 NP_005036.2 P78509

Publications (2)

1
Kainic Acid-Induced Golgi Complex Fragmentation/Dispersal Shifts the Proteolysis of Reelin in Primary Rat Neuronal Cells: An In Vitro Model of Early Stage Epilepsy. Kaneko Y, Sullivan R, Dailey T, Vale FL, Tajiri N, Borlongan CV. Molecular neurobiology. 2016 53:1874-1883. (WB) [Full Text Article] [PubMed:25790952] [PMC:PMC4577368]
2
Rare RELN variants affect Reelin-DAB1 signal transduction in autism spectrum disorder. Sandra M Sánchez-Sánchez, Juliana Magdalon, Karina Griesi-Oliveira, Guilherme L Yamamoto, Carolina Santacruz-Perez, Mariana Fogo, Maria Rita Passos-Bueno, Andrea L Sertié. Human mutation. 2018 October;39:1372-1383. [Full Text Article] [PubMed:29969175]

☰ Filters
Products
Antibodies (68)
Primary (68)
RELN / Reelin (68)
Human (50)
Mouse (12)
Rat (19)
IHC (9)
IHC-Fr (1)
IHC-P (7)
WB (66)
ELISA (7)
ICC (10)
IP (8)
Peptide-ELISA (1)
rabbit (57)
mouse (9)
goat (1)
rat (1)
Product Group
IHCPlus (2)
IgG (15)
IgG1,k (1)
IgG2a (1)
monoclonal mc (10)
polyclonal pc (58)
APC (7)
APC Conjugated (7)
Biotin Conjugated (9)
Cy3 Conjugated (7)
Cy7 Conjugated (7)
FITC Conjugated (9)
HRP Conjugated (8)
PE Conjugated (7)
Unconjugated (14)
aa2400-2610 (16)
aa2398-2608 (10)
aa2086-2296 (8)
aa26-190 (8)
aa3142-3460 (8)
aa3143-3461 (8)
aa164-496 (1)
aa27-861 (1)
aa27-862 (1)
No (68)
Select
RELN / Reelin Goat anti-Mouse Polyclonal (aa27-862) Antibody
Mouse
ELISA, IHC, WB
Unconjugated
100 µg/$962
Select
RELN / Reelin Mouse anti-Mouse Monoclonal (aa164-496) Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µg/$807
RELN / Reelin Antibody - 1:100 staining human Melanoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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RELN / Reelin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
RELN / Reelin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RELN / Reelin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
RELN / Reelin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RELN / Reelin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
RELN / Reelin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RELN / Reelin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
RELN / Reelin Antibody - Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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RELN / Reelin Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
RELN / Reelin Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa26-190) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
RELN / Reelin Rat anti-Mouse Monoclonal (aa27-861) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$872
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Mouse anti-Rat Monoclonal (aa2400-2610) Antibody
Rat
ICC, IP, WB
Unconjugated
100 µl/$323; 200 µl/$371; 500 µl/$531; 1 ml/$617; 2 ml/$850; 5 ml/$1,401
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Mouse anti-Rat Monoclonal (aa2400-2610) (HRP) Antibody
Rat
ICC, IP, WB
HRP Conjugated
100 µl/$356; 200 µl/$419; 500 µl/$642; 1 ml/$801; 2 ml/$1,038; 5 ml/$1,821
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Mouse anti-Rat Monoclonal (aa2400-2610) (Biotin) Antibody
Rat
ICC, IP, WB
Biotin Conjugated
100 µl/$334; 200 µl/$387; 500 µl/$563; 1 ml/$678; 2 ml/$915; 5 ml/$1,541
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Mouse anti-Rat Monoclonal (aa2400-2610) (FITC) Antibody
Rat
ICC, IP, WB
FITC Conjugated
100 µl/$367; 200 µl/$435; 500 µl/$691; 1 ml/$850; 2 ml/$1,096; 5 ml/$1,961
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Mouse anti-Rat Monoclonal (aa2400-2610) (PE) Antibody
Rat
ICC, IP, WB
PE Conjugated
100 µl/$435; 200 µl/$531; 500 µl/$942; 1 ml/$1,112; 2 ml/$1,495; 5 ml/$2,801
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Mouse anti-Rat Monoclonal (aa2400-2610) (APC, Cy7) Antibody
Rat
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$547; 200 µl/$740; 500 µl/$1,281; 1 ml/$1,601; 2 ml/$2,241; 5 ml/$4,201
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Mouse anti-Rat Monoclonal (aa2400-2610) (Cy3) Antibody
Rat
ICC, IP, WB
Cy3 Conjugated
100 µl/$435; 200 µl/$531; 500 µl/$942; 1 ml/$1,112; 2 ml/$1,495; 5 ml/$2,801
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Mouse anti-Rat Monoclonal (aa2400-2610) (APC) Antibody
Rat
ICC, IP, WB
APC Conjugated
100 µl/$435; 200 µl/$531; 500 µl/$942; 1 ml/$1,112; 2 ml/$1,495; 5 ml/$2,801
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
RELN / Reelin Rabbit anti-Mouse Polyclonal (aa3143-3461) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa26-190) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
Select
RELN / Reelin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$351
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa2398-2608) (FITC) Antibody
Human
ICC, WB
FITC Conjugated
100 µl/$328
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa2398-2608) (Biotin) Antibody
Human
ICC, WB
Biotin Conjugated
100 µl/$318
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa2086-2296) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa3142-3460) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
RELN / Reelin Antibody - Western blot of recombinant RELN / Reelin.
Select
RELN / Reelin Rabbit anti-Human Polyclonal (aa2398-2608) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).